Antidepressant Hyperbolic Calculator

Calculate and visualize dynamic hyperbolic tapering schedules for antidepressants based on dose-serotonin transporter occupancy curves.

Antidepressant Information

Antidepressant

Brain Area

Reduction Settings

Starting Dose

Occupancy Reduction (%)

Reduction Preference

Receptor Occupancy Graph
?

Relative Reduction (10%)

Enter a Starting Dose to View Reduction Schedule

The reduction schedule will be calculated based on your current medication dose

About the Calculator

This calculator is aimed to increase awareness about antidepressant hyperbolic tapering by empowering users to compute dose-specific and dynamic discontinuation schedules. Illustrating both dose-occupancy graphs and tapering schedules side-by-side, this tool can help simplify understanding of the hyperbolic tapering method.

The dose-occupancy curves for the antidepressants included in the calculator come from research by Sørensen, Ruhé, & Munkholm, 2022:The relationship between dose and serotonin transporter occupancy of antidepressants—a systematic review

Disclaimer & User Agreement

This calculator is only for informational and educational purposes. It is not a substitute for professional medical advice. The content, including all calculations and outputs, is not intended to guide real-world medical decisions. Do not use this calculator to make any decisions about medication or treatment. Always seek the advice of a physician, pharmacist, or other qualified healthcare provider with any questions you may have regarding a medical condition or medication. While efforts have been made to ensure accuracy, the creators of this website make no guarantees about the correctness or applicability of the results and accept no responsibility for any harm, loss, or damage that may arise from the use of this calculator. By using this tool, you agree to these terms.